MAT(T)ISSE • Bioresorption for reconstruction

Projet FWVL Mat(t)isse

The MAT(T)ISSE project is designing a breast bioprosthesis solution that is entirely non-toxic for the patient.

The project aims to create a new class 3 implantable bioprosthesis to help the body restore the damaged areas following curative surgical procedures. This tissue reconstruction involves taking an autologous sample of fat cells (adipose tissues), which are then reimplanted into a synthetic, resorbable lace-like textile structure.

The resorbable implant will eventually disappear and the patient will be left with a reconstructed breast grown by their own cells.


One in eight women suffer from breast cancer in Europe, making it one of the world’s worst-affected regions.

The most common curative surgery is the mastectomy, a complicated operation undergone by 73% of patients diagnosed with breast cancer. Only 20% of women currently opt for breast reconstruction, of which there are three main methods:

  • silicone breast implants
  • autologous transplant of vascular tissues
  • autologous transplant of non-vascular fatty tissues (lipofilling)

There are numerous disadvantages associated with these methods. Silicone implants, for example, are not risk-free: following a scandal in 2010, Belgium and France recommended that PIP implants be removed.

Key info

Project type: Interreg FWVL

Start date: 1 October 2017

Duration: four years

Total cost: €3,093,067.71

ERDF funding: €1,546,533.83

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